LRRC7

Across TCGA patient cohorts, LRRC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,138 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC7-associated proteins across cancer lineages are PSMB8, NIBAN2, and MGAT1. Each is linked with LRRC7 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRRC7-to-partner and partner-to-LRRC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC7 versus PSMB8 in UCEC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC7→partner) and Y-score (partner→LRRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMB8 →	-0.497	-0.437	<.001	.002	3	3
GBM	NIBAN2 →	-0.384	-0.834	<.001	<.001	3	3
CCRCC	MGAT1 →	-0.340	-0.547	<.001	<.001	3	3
GBM	NBEA →	+0.497	+1.356	<.001	<.001	3	3
PDAC	NCF1 →	-0.592	-0.133	.001	.003	3	3
OV	NEK9_S801 →	+0.995	+0.517	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,138 associations by consensus.

LRRC7 vs PSMB8 — UCEC

Explore this scatter interactively →