LRRC7

Across TCGA patient cohorts, LRRC7 protein abundance is significantly associated with the RNA expression of many other genes, with 3,968 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC7-associated genes across cancer lineages are SNRPD3, GGT1, and PRODH. Each is linked with LRRC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC7-to-partner and partner-to-LRRC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC7 versus SNRPD3 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC7→partner) and Y-score (partner→LRRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.364	+0.368	.008	.007	3	1
GBM	GGT1 →	+0.230	+0.322	<.001	.005	3	1
GBM	PRODH →	+0.830	+0.421	<.001	<.001	3	1
GBM	LGALS1 →	-0.792	-0.423	.001	.001	3	1
GBM	SEPTIN3 →	+1.566	+0.577	<.001	<.001	3	1
GBM	RASL10A →	+1.147	+0.521	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,968 associations by consensus.

LRRC7 vs SNRPD3 — GBM

Explore this scatter interactively →