LRRC7

Across TCGA cell cohorts, LRRC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,972 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC7-associated GO terms across cancer lineages are Neurotransmitter receptor transport, endosome to postsynaptic membrane, Neurotransmitter receptor transport, endosome to plasma membrane, and Regulation of stress fiber assembly. Each is linked with LRRC7 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRRC7-to-partner and partner-to-LRRC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurotransmitter receptor transport, endosome to postsynaptic membrane grouped by LRRC7-low versus LRRC7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC7→partner) and Y-score (partner→LRRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Neurotransmitter receptor transport, endosome to postsynaptic membrane →	-0.133	-0.603	.006	.008	3	7
UPPER_AERODIGESTIVE_TRACT	Neurotransmitter receptor transport, endosome to plasma membrane →	-0.133	-0.603	.006	.008	3	7
SKIN	Regulation of stress fiber assembly →	+0.056	+0.651	<.001	<.001	3	7
KIDNEY	Tubulin deacetylation →	+0.099	+1.147	.001	.001	3	6
SKIN	Regulation of actomyosin structure organization →	+0.056	+0.654	<.001	.002	3	6
BLOOD_Lymphoma	Regulation of cell cycle G1/S phase transition →	+0.040	+0.172	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,972 associations by consensus.

Neurotransmitter receptor transport, endosome to postsynaptic membrane by LRRC7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →