LRRC61

Across TCGA patient cohorts, LRRC61 protein abundance is significantly associated with the RNA expression of many other genes, with 989 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LRRC61-associated genes across cancer lineages are TRAJ61, WIPF1, and HMGB2. Each is linked with LRRC61 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC61-to-partner and partner-to-LRRC61 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC61 versus TRAJ61 in UCEC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC61→partner) and Y-score (partner→LRRC61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ61 →	-1.435	-0.994	.005	.003	3	2
GBM	WIPF1 →	-0.420	-0.553	.007	.002	3	2
CCRCC	HMGB2 →	+0.526	+0.399	<.001	<.001	3	2
LSCC	RNU4-62P →	-0.856	-0.522	.001	.005	3	2
CCRCC	H4C2 →	+0.604	+0.301	.002	.007	3	2
UCEC	ISM2 →	+0.636	+1.255	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 989 associations by consensus.

LRRC61 vs TRAJ61 — UCEC

Explore this scatter interactively →