LRRC59

Across TCGA patient cohorts, LRRC59 protein abundance is significantly associated with the RNA expression of many other genes, with 10,527 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LRRC59-associated genes across cancer lineages are KPNA2, NME1, and SLC35B1. Each is linked with LRRC59 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC59-to-partner and partner-to-LRRC59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC59 versus KPNA2 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC59→partner) and Y-score (partner→LRRC59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KPNA2 →	+0.767	+0.490	<.001	<.001	3	6
BRCA	NME1 →	+0.999	+0.568	<.001	<.001	3	6
OV	SLC35B1 →	+0.627	+0.509	<.001	<.001	3	5
BRCA	RERG →	-1.229	-0.328	<.001	.001	3	5
HNSC	N4BP2L1 →	-0.770	-0.230	<.001	.002	2	6
COAD	SPARCL1 →	-1.104	-0.289	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,527 associations by consensus.

LRRC59 vs KPNA2 — BRCA

Explore this scatter interactively →