LRRC59

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC59 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible LRRC59-associated genes across cancer lineages are CD8+ T-cells and CD8+ Tcm. Each is linked with LRRC59 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC59-to-partner and partner-to-LRRC59 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by LRRC59-low versus LRRC59-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC59→partner) and Y-score (partner→LRRC59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCACD8+ T-cells →+0.025+4.177.010.01431
BLCACD8+ Tcm →+0.066+4.177<.001.01431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by LRRC59 expression — BLCA

Box plot of CD8+ T-cells in LRRC59-low vs LRRC59-high samples in BLCA.

Explore this box plot interactively →

Exploration