LRRC53

Across TCGA patient cohorts, LRRC53 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,678 significant associations in total. LGG shows the largest number of these associations.

The most reproducible LRRC53-associated GO terms across cancer lineages are Transport along microtubule, Microtubule-based transport, and Vesicle targeting. Each is linked with LRRC53 in more than 14 cancer types. Because this analysis shows association rather than direction, both LRRC53-to-partner and partner-to-LRRC53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by LRRC53-low versus LRRC53-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC53→partner) and Y-score (partner→LRRC53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Transport along microtubule →	+0.033	+0.108	<.001	<.001	3	15
UCEC	Microtubule-based transport →	+0.025	+0.083	<.001	.002	2	14
UCEC	Vesicle targeting →	+0.037	+0.118	<.001	<.001	3	13
UCEC	Cytoskeleton-dependent intracellular transport →	+0.029	+0.126	<.001	<.001	3	12
STAD	Regulation of microtubule polymerization or depolymerization →	+0.048	+0.048	<.001	.002	2	13
STAD	Autophagy of mitochondrion →	+0.069	+0.087	<.001	.004	1	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,678 associations by consensus.

Transport along microtubule by LRRC53 expression — UCEC

Explore this box plot interactively →