LRRC4C

Across TCGA cell cohorts, LRRC4C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,256 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRRC4C-associated GO terms across cancer lineages are Heart contraction, Translational initiation, and DNA-templated transcription elongation. Each is linked with LRRC4C in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC4C-to-partner and partner-to-LRRC4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heart contraction grouped by LRRC4C-low versus LRRC4C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC4C→partner) and Y-score (partner→LRRC4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heart contraction →	-0.081	-2.204	<.001	<.001	3	6
BONE	Translational initiation →	+0.048	+1.826	.005	<.001	3	6
OVARY	DNA-templated transcription elongation →	+0.059	+0.687	.003	.001	3	5
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+2.683	<.001	<.001	3	5
BONE	Regulation of base-excision repair →	+0.109	+2.130	<.001	.001	3	5
BONE	Aerobic electron transport chain →	+0.073	+1.776	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,256 associations by consensus.

Heart contraction by LRRC4C expression — BONE

Explore this box plot interactively →