LRRC47

Across TCGA cell cohorts, LRRC47 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,351 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC47-associated GO terms across cancer lineages are Regulation of telomerase RNA localization to Cajal body, Nucleic acid transport, and RNA transport. Each is linked with LRRC47 in more than 15 cancer types. Because this analysis shows association rather than direction, both LRRC47-to-partner and partner-to-LRRC47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomerase RNA localization to Cajal body grouped by LRRC47-low versus LRRC47-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC47→partner) and Y-score (partner→LRRC47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.102	+0.711	<.001	<.001	3	16
OESOPHAGUS	Nucleic acid transport →	+0.102	+0.686	.002	.001	3	16
OESOPHAGUS	RNA transport →	+0.102	+0.686	.002	.001	3	16
OESOPHAGUS	mRNA transport →	+0.114	+0.707	.003	<.001	3	16
OESOPHAGUS	Nuclear export →	+0.094	+0.640	.003	.005	3	16
BONE	RNA localization →	+0.089	+0.732	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,351 associations by consensus.

Regulation of telomerase RNA localization to Cajal body by LRRC47 expression — BONE

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