LRRC47

Across TCGA pan-cancer cohorts, LRRC47 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LRRC47’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LRRC47 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRRC47 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, KICH, and THCA are the cancer types where LRRC47 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC47 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.492	<.001	10	view →
KICH	Female	All	−0.988	<.001	9	view →
THCA	Male	III,IV	−0.461	<.001	8	view →
LUSC	Male	II,III,IV	+0.599	<.001	7	view →
LIHC	Male	All	+0.362	<.001	6	view →
HNSC	All	All	+0.283	.002	6	view →
STAD	Male	II,III,IV	+0.807	.006	4	view →
KIRC	Male	II,III,IV	−0.243	.023	3	view →
CHOL	All	All	+0.683	.002	2	view →
KIRP	Male	All	−0.356	.011	2	view →
UCEC	All	All	−0.326	.044	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LRRC47–COAD

Open the COAD breakdown →