LRRC47

Across TCGA cell cohorts, LRRC47 mutation is significantly associated with the mutation status of many other genes, with 3,680 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRRC47-associated genes across cancer lineages are ATP8A2, GOLGA1, and RTP1. Each is linked with LRRC47 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRRC47-to-partner and partner-to-LRRC47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP8A2 grouped by LRRC47-low versus LRRC47-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC47→partner) and Y-score (partner→LRRC47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ATP8A2 →	+4.614	+4.614	.006	.006	1	3
CNS	GOLGA1 →	+5.614	+5.044	.003	.003	1	3
CNS	RTP1 →	+4.614	+5.584	<.001	<.001	1	3
BLOOD_Leukemia	ARHGAP29 →	+2.870	+3.347	.009	.009	1	3
BLOOD_Leukemia	CDH22 →	+3.063	+3.498	.006	.006	1	3
BREAST	MAGEE2 →	+5.297	+5.297	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,680 associations by consensus.

ATP8A2 by LRRC47 expression — CNS

Explore this box plot interactively →