LRRC41

Across TCGA patient cohorts, LRRC41 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC41-associated proteins across cancer lineages are ZMYM4, SMARCA4, and KHDRBS1. Each is linked with LRRC41 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC41-to-partner and partner-to-LRRC41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC41 versus ZMYM4 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC41→partner) and Y-score (partner→LRRC41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZMYM4 →	+0.412	+0.371	<.001	<.001	3	5
LSCC	SMARCA4 →	+0.478	+0.474	<.001	<.001	3	4
GBM	KHDRBS1 →	+0.244	+0.228	.003	.002	3	4
LSCC	YTHDF2 →	+0.236	+0.375	.003	.004	3	4
HNSC	MZB1 →	-0.899	-0.371	<.001	<.001	3	3
HNSC	SEC11C →	-0.913	-0.349	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,006 associations by consensus.

LRRC41 vs ZMYM4 — GBM

Explore this scatter interactively →