LRRC40

Across TCGA patient cohorts, LRRC40 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,486 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC40-associated proteins across cancer lineages are WDFY4, WRNIP1, and MCM3. Each is linked with LRRC40 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC40-to-partner and partner-to-LRRC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC40 versus WDFY4 in CCRCC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC40→partner) and Y-score (partner→LRRC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	WDFY4 →	-0.434	-0.380	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.319	+0.331	<.001	<.001	3	5
UCEC	MCM3 →	+0.589	+0.457	<.001	<.001	3	5
LUAD	MCM5 →	+0.672	+0.280	<.001	.006	3	5
LSCC	MCM7 →	+0.565	+0.460	.001	.001	3	5
COAD	MLYCD →	-0.290	-0.592	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,486 associations by consensus.

LRRC40 vs WDFY4 — CCRCC

Explore this scatter interactively →