LRRC37BP1

Across TCGA patient cohorts, LRRC37BP1 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC37BP1-associated genes across cancer lineages are RNA5SP222, MIR6794, and AMY1C. Each is linked with LRRC37BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC37BP1-to-partner and partner-to-LRRC37BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP222 grouped by LRRC37BP1-low versus LRRC37BP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37BP1→partner) and Y-score (partner→LRRC37BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP222 →	+0.316	+4.877	<.001	.003	3	2
BLCA	MIR6794 →	+0.447	+7.640	<.001	.009	3	1
LGG	AMY1C →	+0.029	+7.977	<.001	.007	3	1
LGG	RNU6-99P →	+0.364	+7.977	<.001	.007	3	1
LUAD	OR5BE1P →	+0.029	+7.930	<.001	.008	3	1
LUAD	RNU7-88P →	+0.351	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

RNA5SP222 by LRRC37BP1 expression — UCEC

Explore this box plot interactively →