LRRC37B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC37B mutation is significantly associated with the RNA expression of many other genes, with 1,753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC37B-associated genes across cancer lineages are FAM162B, LONP1, and RNA5SP358. Each is linked with LRRC37B in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC37B-to-partner and partner-to-LRRC37B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37B→partner) and Y-score (partner→LRRC37B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFAM162B →-0.537-2.785.001.00332
UCECLONP1 →+0.498+3.201<.001<.00132
UCECRNA5SP358 →+0.191+2.061.001.00432
UCECTRAJ12 →+0.615+2.166<.001<.00132
UCECRNU6-918P →+0.242+2.219<.001.00532
UCECGAPDHP72 →+0.343+1.917.009.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,753 associations by consensus.

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