LRRC37A6P

Across TCGA pan-cancer cohorts, LRRC37A6P RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LRRC37A6P data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher LRRC37A6P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC37A6P expression acts as an unfavorable survival marker, although some lineages such as LAML and KIRP show a favorable association.

LGG, UVM, and KICH are the cancer types where LRRC37A6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.645	0.818	<.001	45	view →
UVM	DFS	Quartile	All	0.377	1.000	.006	40	view →
KICH	OS	Quartile	II,III,IV	0.200	1.000	.004	29	view →
LAML	DFS	Median	All	0.568	0.247	.002	28	view →
LIHC	OS	Quartile	All	0.654	0.878	<.001	28	view →
BRCA	OS	Median	All	0.476	0.674	<.001	27	view →
DLBC	DFS	Tertile	All	0.540	1.000	.001	23	view →
KIRP	DFS	Quartile	All	0.844	0.564	.025	22	view →
OV	DFS	Tertile	IV	0.556	0.275	.002	18	view →
UCEC	DFS	Tertile	All	0.497	0.821	.003	18	view →
ACC	DFS	Median	II,III,IV	0.187	0.573	.014	17	view →
STAD	DFS	Quartile	II,III,IV	0.525	0.708	.021	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

LRRC37A6P–LGG (DFS)

Open the LGG breakdown →