LRRC37A3

Across TCGA cell cohorts, LRRC37A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,173 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRRC37A3-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with LRRC37A3 in more than 14 cancer types. Because this analysis shows association rather than direction, both LRRC37A3-to-partner and partner-to-LRRC37A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by LRRC37A3-low versus LRRC37A3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37A3→partner) and Y-score (partner→LRRC37A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+0.898	.002	.003	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.102	+0.887	.001	<.001	3	15
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.106	+0.972	.001	.001	3	15
LUNG_SCLC	Target-directed miRNA degradation →	+0.114	+0.781	<.001	.005	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.093	+0.680	<.001	<.001	3	14
STOMACH	Process utilizing autophagic mechanism →	+0.072	+0.837	.001	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,173 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by LRRC37A3 expression — STOMACH

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