LRRC37A15P

Across TCGA pan-cancer cohorts, LRRC37A15P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LRRC37A15P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LRRC37A15P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC37A15P expression acts as an unfavorable survival marker, although some lineages such as KIRC and GBM show a favorable association.

CESC, KIRC, and MESO are the cancer types where LRRC37A15P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.770	0.875	<.001	56	view →
KIRC	DFS	Median	All	0.874	0.715	.001	50	view →
MESO	OS	Quartile	II,III,IV	0.273	0.542	.010	38	view →
KIRP	DFS	Tertile	All	0.787	0.920	.004	38	view →
BLCA	DFS	Tertile	All	0.474	0.766	.001	31	view →
LGG	DFS	Quartile	All	0.716	0.864	<.001	27	view →
GBM	OS	Tertile	All	0.568	0.288	.007	26	view →
LUSC	DFS	Median	III,IV	0.339	0.968	<.001	24	view →
UCS	DFS	Tertile	IV	0.956	0.422	.024	24	view →
LIHC	DFS	Quartile	All	0.427	0.599	.008	19	view →
ACC	OS	Tertile	IV	0.901	0.390	.006	19	view →
SKCM	OS	Median	III,IV	0.471	0.306	.002	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LRRC37A15P–CESC (DFS)

Open the CESC breakdown →