LRRC37A15P

Across TCGA pan-cancer cohorts, LRRC37A15P RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LRRC37A15P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LRRC37A15P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRRC37A15P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, HNSC, and KIRP are the cancer types where LRRC37A15P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC37A15P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.389	<.001	11	view →
HNSC	Female	II,III,IV	+0.363	<.001	11	view →
KIRP	Female	All	+0.307	.010	6	view →
THCA	All	II,III,IV	−0.292	<.001	6	view →
BLCA	Female	All	+0.265	.011	6	view →
COAD	All	All	+0.208	.002	6	view →
STAD	Male	II,III,IV	+0.432	<.001	5	view →
CHOL	Male	All	+0.500	<.001	4	view →
BRCA	All	All	+0.336	<.001	4	view →
READ	Male	All	+0.290	.025	2	view →
LIHC	All	All	+0.081	.009	2	view →
LUAD	All	All	+0.278	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LRRC37A15P–KIRC

Open the KIRC breakdown →