Across TCGA pan-cancer cohorts, LRRC37A11P RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LRRC37A11P data layer compared with 1 for mutation status.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LRRC37A11P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LRRC37A11P expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.
KIRC, LIHC, and STAD are the cancer types where LRRC37A11P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.