LRRC36

Across TCGA cell cohorts, LRRC36 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,770 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC36-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Sodium ion transmembrane transport, and Mitotic cytokinesis. Each is linked with LRRC36 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRRC36-to-partner and partner-to-LRRC36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by LRRC36-low versus LRRC36-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC36→partner) and Y-score (partner→LRRC36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of syncytium formation by plasma membrane fusion →	+0.076	+0.287	<.001	.004	3	9
CNS	Sodium ion transmembrane transport →	-0.042	-0.247	<.001	.004	3	7
BREAST	Mitotic cytokinesis →	+0.053	+0.256	.006	.003	2	8
OVARY	Aerobic respiration →	+0.081	+0.396	.003	<.001	2	7
LUNG_NSCLC_LUAD	Sodium ion transport →	-0.049	-0.452	<.001	.003	3	6
SKIN	Potassium ion transmembrane transport →	-0.059	-0.300	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,770 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by LRRC36 expression — BREAST

Explore this box plot interactively →