Across TCGA cell cohorts, LRRC30 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRRC30-associated genes across cancer lineages are PRAMEF20, OR5M10, and PAX4. Each is linked with LRRC30 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC30-to-partner and partner-to-LRRC30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC30→partner) and Y-score (partner→LRRC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1
BLOOD_Lymphoma	OR5M10 →	+0.014	+4.643	<.001	.005	3	1
CNS	PAX4 →	+0.025	+4.832	<.001	.002	3	1
CNS	OR52N5 →	+0.009	+4.754	<.001	.005	3	1
CNS	DCANP1 →	+0.006	+4.643	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

LRRC30 survival (RNA) · tumor vs normal (RNA) · all LRRC30 data types