LRRC3-DT

Across TCGA patient cohorts, LRRC3-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,114 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LRRC3-DT-associated GO terms across cancer lineages are Regulation of protein folding, Proton motive force-driven ATP synthesis, and Protein stabilization. Each is linked with LRRC3-DT in more than 18 cancer types. Because this analysis shows association rather than direction, both LRRC3-DT-to-partner and partner-to-LRRC3-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein folding grouped by LRRC3-DT-low versus LRRC3-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC3-DT→partner) and Y-score (partner→LRRC3-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein folding →	+0.046	+0.207	<.001	<.001	3	19
STAD	Proton motive force-driven ATP synthesis →	+0.051	+0.132	<.001	<.001	3	18
STAD	Protein stabilization →	+0.046	+0.215	<.001	<.001	3	17
STAD	Nucleoside triphosphate biosynthetic process →	+0.048	+0.188	<.001	<.001	3	17
STAD	ATP biosynthetic process →	+0.050	+0.171	<.001	<.001	3	17
STAD	Macromolecule deacylation →	+0.038	+0.182	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,114 associations by consensus.

Regulation of protein folding by LRRC3-DT expression — STAD

Explore this box plot interactively →