LRRC24

Across TCGA patient cohorts, LRRC24 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,085 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LRRC24-associated GO terms across cancer lineages are Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tRNA thio-modification, and Protein polyglutamylation. Each is linked with LRRC24 in more than 15 cancer types. Because this analysis shows association rather than direction, both LRRC24-to-partner and partner-to-LRRC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence grouped by LRRC24-low versus LRRC24-high in PCPG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC24→partner) and Y-score (partner→LRRC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.042	+0.299	<.001	<.001	3	16
LGG	tRNA thio-modification →	+0.036	+0.149	<.001	<.001	3	13
PAAD	Protein polyglutamylation →	+0.033	+0.082	<.001	<.001	3	13
PCPG	Tail-anchored membrane protein insertion into ER membrane →	+0.024	+0.176	<.001	<.001	3	12
SCLC	Regulation of synaptic vesicle membrane organization →	+0.474	+1.096	<.001	<.001	3	10
SCLC	Neutrophil chemotaxis →	-0.120	-1.026	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,085 associations by consensus.

Protein insertion into ER membrane by stop-transfer membrane-anchor sequence by LRRC24 expression — PCPG

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