LRRC23

Across TCGA cell cohorts, LRRC23 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,277 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible LRRC23-associated GO terms across cancer lineages are Radial spoke assembly, COPII-coated vesicle budding, and Cilium movement involved in cell motility. Each is linked with LRRC23 in more than 19 cancer types. Because this analysis shows association rather than direction, both LRRC23-to-partner and partner-to-LRRC23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Radial spoke assembly grouped by LRRC23-low versus LRRC23-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC23→partner) and Y-score (partner→LRRC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Radial spoke assembly →	+1.292	+1.052	<.001	<.001	3	20
STOMACH	COPII-coated vesicle budding →	+0.111	+1.124	.001	.002	3	10
KIDNEY	Cilium movement involved in cell motility →	-0.094	-1.274	<.001	<.001	3	10
KIDNEY	Sperm motility →	-0.093	-1.142	<.001	<.001	3	10
KIDNEY	Flagellated sperm motility →	-0.093	-1.142	<.001	<.001	3	10
LIVER	Protein localization to cilium →	+0.062	+1.172	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,277 associations by consensus.

Radial spoke assembly by LRRC23 expression — OESOPHAGUS

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