LRRC20

Across TCGA patient cohorts, LRRC20 protein abundance is significantly associated with the RNA expression of many other genes, with 9,998 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LRRC20-associated genes across cancer lineages are ARHGEF9, EIF4EBP2, and ADK. Each is linked with LRRC20 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRC20-to-partner and partner-to-LRRC20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC20 versus ARHGEF9 in GBM, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC20→partner) and Y-score (partner→LRRC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGEF9 →	+0.560	+0.226	<.001	<.001	3	4
GBM	EIF4EBP2 →	+0.557	+0.454	<.001	<.001	3	4
LUAD	ADK →	+0.558	+0.350	<.001	<.001	3	4
LSCC	PPP1R9A →	+0.849	+0.173	<.001	.007	3	4
UCEC	USP54 →	+0.781	+0.482	<.001	<.001	3	4
GBM	KBTBD3 →	+0.432	+0.275	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,998 associations by consensus.

LRRC20 vs ARHGEF9 — GBM

Explore this scatter interactively →