LRRC15

Across TCGA cell cohorts, LRRC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,261 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRRC15-associated GO terms across cancer lineages are Dentinogenesis, Positive regulation of protein exit from endoplasmic reticulum, and Positive regulation of stress fiber assembly. Each is linked with LRRC15 in more than 10 cancer types. Because this analysis shows association rather than direction, both LRRC15-to-partner and partner-to-LRRC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by LRRC15-low versus LRRC15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC15→partner) and Y-score (partner→LRRC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dentinogenesis →	+2.491	+2.635	<.001	<.001	3	11
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.154	+2.789	<.001	<.001	3	11
BONE	Positive regulation of stress fiber assembly →	+0.173	+2.112	<.001	<.001	3	9
BONE	COPII-coated vesicle cargo loading →	+0.098	+1.870	<.001	.001	3	9
BONE	Regulation of plasminogen activation →	+0.246	+1.988	<.001	<.001	3	8
BONE	Positive regulation of supramolecular fiber organization →	+0.082	+2.108	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,261 associations by consensus.

Dentinogenesis by LRRC15 expression — BONE

Explore this box plot interactively →