Across TCGA patient cohorts, LRRC10B mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC10B-associated genes across cancer lineages are RN7SKP128, RNU6-996P, and MIR539. Each is linked with LRRC10B in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC10B-to-partner and partner-to-LRRC10B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC10B→partner) and Y-score (partner→LRRC10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP128 →	+0.538	+7.741	<.001	.009	3	1
COAD	RNU6-996P →	+0.357	+7.741	<.001	.009	3	1
COAD	MIR539 →	+0.601	+7.741	<.001	.009	3	1
COAD	MIR655 →	+0.383	+7.741	<.001	.009	3	1
COAD	RNU6-1246P →	+1.377	+7.741	<.001	.009	3	1
COAD	RNU6-325P →	+0.359	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

LRRC10B survival (RNA) · tumor vs normal (RNA) · all LRRC10B data types