Across TCGA patient cohorts, LRRC10 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,680 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LRRC10-associated GO terms across cancer lineages are Regulation of double-strand break repair, Obsolete histone modification, and Cell cycle G2/M phase transition. Each is linked with LRRC10 in more than 12 cancer types. Because this analysis shows association rather than direction, both LRRC10-to-partner and partner-to-LRRC10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC10→partner) and Y-score (partner→LRRC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair →	+0.063	+0.141	<.001	.009	2	13
SCLC	Obsolete histone modification →	+0.124	+0.723	<.001	<.001	3	11
SCLC	Cell cycle G2/M phase transition →	+0.065	+0.366	.001	.002	3	11
SCLC	Positive regulation of DNA repair →	+0.072	+0.462	<.001	<.001	3	11
SCLC	Negative regulation of gene expression, epigenetic →	+0.085	+0.403	<.001	<.001	3	11
STAD	Regulation of mRNA catabolic process →	+0.057	+0.105	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,680 associations by consensus.

Exploration

LRRC10 survival (RNA) · tumor vs normal (RNA) · all LRRC10 data types