Across TCGA pan-cancer cohorts, LRRC10 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LRRC10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LRRC10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRRC10 is over-expressed in tumor.

KIRC, KIRP, and HNSC are the cancer types where LRRC10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.009	.005	5	view →
KIRP	All	All	+0.010	.026	1	view →
HNSC	All	All	+0.008	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: LRRC10 RNA expression & survival · all LRRC10 data types