Across TCGA cell cohorts, LRRC10 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LRRC10-associated genes across cancer lineages are GLT6D1, BMP15, and OR10G2. Each is linked with LRRC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC10-to-partner and partner-to-LRRC10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC10→partner) and Y-score (partner→LRRC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GLT6D1 →	+0.409	+5.196	<.001	.005	3	1
BREAST	BMP15 →	+0.012	+4.781	<.001	.003	3	1
BREAST	OR10G2 →	+0.135	+4.672	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

LRRC10 survival (RNA) · tumor vs normal (RNA) · all LRRC10 data types