LRPPRC

Across TCGA patient cohorts, LRPPRC RNA expression is significantly associated with the protein abundance of many other proteins, with 21,505 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRPPRC-associated proteins across cancer lineages are MSH2, RRM2, and ORC5. Each is linked with LRPPRC in more than 8 cancer types. Because this analysis shows association rather than direction, both LRPPRC-to-partner and partner-to-LRPPRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRPPRC versus MSH2 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRPPRC→partner) and Y-score (partner→LRPPRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH2 →	+0.697	+0.798	<.001	<.001	3	9
HNSC	RRM2 →	+0.666	+0.937	<.001	<.001	3	8
LSCC	ORC5 →	+0.370	+0.667	<.001	<.001	3	8
LSCC	ORC3 →	+0.376	+0.694	<.001	<.001	3	8
HNSC	PUS7 →	+0.495	+0.660	<.001	<.001	3	8
GBM	SMC2 →	+0.797	+0.323	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,505 associations by consensus.

LRPPRC vs MSH2 — LSCC

Explore this scatter interactively →