LRPPRC

Across TCGA patient cohorts, LRPPRC protein abundance is significantly associated with the RNA expression of many other genes, with 20,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRPPRC-associated genes across cancer lineages are DCN, MT-CO3, and IFFO1. Each is linked with LRPPRC in more than 8 cancer types. Because this analysis shows association rather than direction, both LRPPRC-to-partner and partner-to-LRPPRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRPPRC versus DCN in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRPPRC→partner) and Y-score (partner→LRPPRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DCN →	-1.309	-0.289	<.001	<.001	3	9
HNSC	MT-CO3 →	+0.814	+0.380	<.001	<.001	3	9
OV	IFFO1 →	-0.731	-0.374	<.001	<.001	3	8
OV	DOCK8 →	-0.964	-0.405	<.001	<.001	3	8
COAD	C7 →	-1.817	-0.555	<.001	<.001	3	8
OV	PDE1B →	-0.746	-0.357	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,966 associations by consensus.

LRPPRC vs DCN — OV

Explore this scatter interactively →