LRPPRC

Across TCGA patient cohorts, LRPPRC protein abundance is significantly associated with the protein abundance of many other proteins, with 26,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRPPRC-associated proteins across cancer lineages are HSPE1, IARS2, and LARS2. Each is linked with LRPPRC in more than 9 cancer types. Because this analysis shows association rather than direction, both LRPPRC-to-partner and partner-to-LRPPRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRPPRC versus HSPE1 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRPPRC→partner) and Y-score (partner→LRPPRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPE1 →	+0.662	+0.281	<.001	<.001	3	10
COAD	IARS2 →	+0.473	+0.534	<.001	<.001	3	10
OV	LARS2 →	+0.463	+0.479	<.001	<.001	3	10
BRCA	LONP1 →	+0.456	+0.514	<.001	<.001	3	10
BRCA	AFG3L2 →	+0.585	+0.505	<.001	<.001	3	10
LSCC	DAP3 →	+0.537	+0.625	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,177 associations by consensus.

LRPPRC vs HSPE1 — HNSC

Explore this scatter interactively →