LRPAP1

Across TCGA pan-cancer cohorts, LRPAP1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated LRPAP1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LRPAP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated LRPAP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where LRPAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.900	1.000	.005	36	view →
LSCC	DFS	Tertile	II,III,IV	0.544	0.880	.007	17	view →
LUAD	DFS	Median	All	0.843	0.955	.009	15	view →
COAD	DFS	Median	All	1.000	0.888	.023	12	view →
PDAC	OS	Median	IV	0.951	0.381	.006	12	view →
HNSC	OS	Quartile	All	0.318	1.000	.036	6	view →
GBM	OS	Median	All	0.775	0.853	.020	2	view →
CCRCC	DFS	Tertile	III,IV	0.545	0.779	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

LRPAP1–UCEC (OS)

Open the UCEC breakdown →