LRPAP1

Across TCGA cell cohorts, LRPAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,076 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRPAP1-associated GO terms across cancer lineages are Protein insertion into ER membrane, Endoplasmic reticulum organization, and Lysosome organization. Each is linked with LRPAP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both LRPAP1-to-partner and partner-to-LRPAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane grouped by LRPAP1-low versus LRPAP1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRPAP1→partner) and Y-score (partner→LRPAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein insertion into ER membrane →	+0.081	+0.860	<.001	.002	3	15
BONE	Endoplasmic reticulum organization →	+0.097	+1.245	<.001	<.001	3	15
BONE	Lysosome organization →	+0.060	+1.070	<.001	<.001	3	14
BONE	Lytic vacuole organization →	+0.060	+1.070	<.001	<.001	3	14
LUNG_SCLC	Multi-pass transmembrane protein insertion into ER membrane →	+0.144	+0.916	<.001	<.001	3	14
BONE	Endoplasmic reticulum to cytosol transport →	+0.145	+1.190	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,076 associations by consensus.

Protein insertion into ER membrane by LRPAP1 expression — SOFT_TISSUE

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