LRP5L

Across TCGA patient cohorts, LRP5L protein abundance is significantly associated with the RNA expression of many other genes, with 18,018 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRP5L-associated genes across cancer lineages are RASAL3, LY9, and ARHGAP9. Each is linked with LRP5L in more than 8 cancer types. Because this analysis shows association rather than direction, both LRP5L-to-partner and partner-to-LRP5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP5L versus RASAL3 in HNSC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP5L→partner) and Y-score (partner→LRP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RASAL3 →	+0.887	+0.824	<.001	<.001	3	9
LUAD	LY9 →	+0.927	+0.658	<.001	.007	3	9
BRCA	ARHGAP9 →	+1.115	+0.977	<.001	<.001	3	9
LUAD	ZNF831 →	+0.963	+0.681	<.001	<.001	3	9
HNSC	FAM78A →	+0.908	+0.801	<.001	<.001	3	9
LUAD	GFI1 →	+0.875	+0.875	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,018 associations by consensus.

LRP5L vs RASAL3 — HNSC

Explore this scatter interactively →