LRP5L

Across TCGA cell cohorts, LRP5L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,426 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRP5L-associated GO terms across cancer lineages are Chiasma assembly, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with LRP5L in more than 12 cancer types. Because this analysis shows association rather than direction, both LRP5L-to-partner and partner-to-LRP5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chiasma assembly grouped by LRP5L-low versus LRP5L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP5L→partner) and Y-score (partner→LRP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chiasma assembly →	+0.389	+1.354	.001	<.001	3	13
OVARY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.103	+0.781	<.001	<.001	3	12
OVARY	Symbiont-mediated disruption of host anatomical structure →	+0.103	+0.781	<.001	<.001	3	12
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.158	+1.047	<.001	<.001	3	12
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.219	+1.532	.001	.001	3	12
BONE	DNA topological change →	+0.161	+1.277	.002	.005	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,426 associations by consensus.

Chiasma assembly by LRP5L expression — BONE

Explore this box plot interactively →