LRP4-AS1

Across TCGA pan-cancer cohorts, LRP4-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LRP4-AS1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher LRP4-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LRP4-AS1 expression acts as an unfavorable survival marker, although some lineages such as DLBC and THCA show a favorable association.

DLBC, KICH, and LIHC are the cancer types where LRP4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Quartile	All	1.000	0.506	.002	47	view →
KICH	OS	Quartile	All	0.612	1.000	.001	46	view →
LIHC	DFS	Quartile	All	0.344	0.520	.001	32	view →
THCA	OS	Median	II,III,IV	1.000	0.542	.002	30	view →
KIRP	DFS	Tertile	All	0.561	0.787	<.001	29	view →
BRCA	OS	Tertile	IV	0.382	0.853	.007	25	view →
LUSC	OS	Median	All	0.720	0.598	.003	24	view →
HNSC	DFS	Median	III,IV	0.610	0.742	.003	21	view →
ACC	OS	Tertile	II,III,IV	0.222	0.838	.003	21	view →
UVM	DFS	Quartile	All	0.772	0.340	.009	19	view →
SARC	DFS	Tertile	All	0.507	0.680	.002	18	view →
PRAD	DFS	Tertile	All	0.838	0.940	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LRP4-AS1–DLBC (DFS)

Open the DLBC breakdown →