LRP2

Across TCGA patient cohorts, LRP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,752 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRP2-associated proteins across cancer lineages are LRP2_S4616, LRP2_S4463, and LRP2_T4565. Each is linked with LRP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRP2-to-partner and partner-to-LRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP2 versus LRP2_S4616 in GBM, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP2→partner) and Y-score (partner→LRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LRP2_S4616 →	+1.520	+3.433	.001	<.001	3	6
UCEC	LRP2_S4463 →	+3.190	+3.336	<.001	<.001	3	5
CCRCC	LRP2_T4565 →	+1.519	+2.514	<.001	<.001	3	5
UCEC	FOXA1_S331 →	+1.709	+1.919	<.001	<.001	3	5
GBM	ENPP4 →	+0.612	+1.112	<.001	<.001	3	5
GBM	SH3BGRL2 →	+0.512	+1.428	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,752 associations by consensus.

LRP2 vs LRP2_S4616 — GBM

Explore this scatter interactively →