LRP1B

Across TCGA cell cohorts, LRP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,276 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRP1B-associated GO terms across cancer lineages are DNA-templated transcription elongation, RNA catabolic process, and mRNA catabolic process. Each is linked with LRP1B in more than 7 cancer types. Because this analysis shows association rather than direction, both LRP1B-to-partner and partner-to-LRP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription elongation grouped by LRP1B-low versus LRP1B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP1B→partner) and Y-score (partner→LRP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA-templated transcription elongation →	+0.082	+0.751	.001	.006	3	7
BONE	RNA catabolic process →	+0.062	+1.420	.002	<.001	3	7
LUNG_NSCLC_LUSC	mRNA catabolic process →	+0.059	+0.835	<.001	.008	3	7
LIVER	Nuclear-transcribed mRNA catabolic process →	+0.048	+0.738	.001	.002	3	7
CNS	Regulation of intracellular transport →	+0.048	+0.776	<.001	<.001	3	7
BONE	Nucleic acid catabolic process →	+0.045	+1.014	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

DNA-templated transcription elongation by LRP1B expression — LIVER

Explore this box plot interactively →