LRP11

Across TCGA pan-cancer cohorts, LRP11 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LRP11 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LRP11 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated LRP11 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, LUAD, and GBM are the cancer types where LRP11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.994	0.678	.007	13	view →
LUAD	OS	Median	II,III,IV	0.443	0.794	.011	13	view →
GBM	DFS	Median	All	0.814	0.660	.013	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

LRP11–HNSC (OS)

Open the HNSC breakdown →