LRP11

Across TCGA patient cohorts, LRP11 protein abundance is significantly associated with the RNA expression of many other genes, with 7,604 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRP11-associated genes across cancer lineages are FLNA, ADGRE5, and HK3. Each is linked with LRP11 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRP11-to-partner and partner-to-LRP11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP11 versus FLNA in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP11→partner) and Y-score (partner→LRP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FLNA →	-1.107	-0.528	.001	<.001	3	4
LSCC	ADGRE5 →	-0.687	-0.654	<.001	<.001	3	4
LSCC	HK3 →	-0.923	-0.550	<.001	.001	3	4
BRCA	TOB1 →	+1.190	+0.545	<.001	.008	3	3
UCEC	GBGT1 →	-0.697	-0.704	.003	.001	3	3
UCEC	RPL7L1P9 →	-0.911	-0.564	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,604 associations by consensus.

LRP11 vs FLNA — UCEC

Explore this scatter interactively →