LRP11

Across TCGA cell cohorts, LRP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRP11-associated GO terms across cancer lineages are Response to water, Intracellular receptor signaling pathway, and Macroautophagy. Each is linked with LRP11 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRP11-to-partner and partner-to-LRP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to water grouped by LRP11-low versus LRP11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP11→partner) and Y-score (partner→LRP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to water →	+0.213	+0.954	.001	.006	2	12
OESOPHAGUS	Intracellular receptor signaling pathway →	+0.059	+0.953	.001	.001	3	10
LUNG_SCLC	Macroautophagy →	+0.047	+0.836	.003	.006	3	10
BLOOD_Lymphoma	Positive regulation of plasma membrane repair →	+0.311	+1.358	.001	<.001	3	9
CNS	Lactose metabolic process →	+0.241	+1.133	.007	<.001	3	9
CNS	Positive regulation of respiratory burst →	-0.149	-0.736	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

Response to water by LRP11 expression — LUNG_NSCLC_LUSC

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