Across TCGA cell cohorts, LRP10 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRP10-associated genes across cancer lineages are OTOR, P2RY13, and GPR148. Each is linked with LRP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRP10-to-partner and partner-to-LRP10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP10→partner) and Y-score (partner→LRP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OTOR →	+0.030	+5.087	<.001	.004	3	1
SKIN	P2RY13 →	+0.004	+3.099	<.001	.002	3	1
OVARY	GPR148 →	+0.054	+4.095	<.001	.003	3	1
LARGE_INTESTINE	TIFAB →	+0.004	+3.977	<.001	.001	3	1
LARGE_INTESTINE	WSCD2 →	+0.128	+3.660	.001	.005	3	1
BLOOD_Leukemia	SLC32A1 →	+0.588	+3.901	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

LRP10 survival (RNA) · tumor vs normal (RNA) · all LRP10 data types