LRIG2-DT

Across TCGA patient cohorts, LRIG2-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,793 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LRIG2-DT-associated proteins across cancer lineages are MAPK13, COG1, and HID1. Each is linked with LRIG2-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both LRIG2-DT-to-partner and partner-to-LRIG2-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRIG2-DT versus MAPK13 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG2-DT→partner) and Y-score (partner→LRIG2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAPK13 →	-0.423	-0.358	<.001	.007	3	5
BRCA	COG1 →	-0.304	-0.335	<.001	<.001	3	4
BRCA	HID1 →	-0.609	-0.271	<.001	<.001	3	4
PDAC	OCLN →	-0.443	-0.233	.001	.005	3	3
LUAD	RAP1GAP →	-0.481	-0.318	.005	.005	2	4
UCEC	ARFGEF3 →	-0.555	-1.158	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,793 associations by consensus.

LRIG2-DT vs MAPK13 — GBM

Explore this scatter interactively →