LRIG1

Across TCGA cell cohorts, LRIG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,097 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRIG1-associated GO terms across cancer lineages are Otolith morphogenesis, Otolith development, and Regulation of gastrulation. Each is linked with LRIG1 in more than 15 cancer types. Because this analysis shows association rather than direction, both LRIG1-to-partner and partner-to-LRIG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Otolith morphogenesis grouped by LRIG1-low versus LRIG1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG1→partner) and Y-score (partner→LRIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Otolith morphogenesis →	+1.470	+2.715	<.001	<.001	3	16
STOMACH	Otolith development →	+0.193	+3.083	<.001	<.001	3	13
SOFT_TISSUE	Regulation of gastrulation →	-0.181	-2.404	<.001	<.001	3	9
OVARY	Regulation of stem cell population maintenance →	+0.063	+1.774	.002	.001	3	9
OVARY	Positive regulation of gastrulation →	-0.215	-1.293	<.001	.005	3	9
BLOOD_Leukemia	Transcription initiation at RNA polymerase II promoter →	+0.049	+1.541	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,097 associations by consensus.

Otolith morphogenesis by LRIG1 expression — BLOOD_Myeloma

Explore this box plot interactively →