LRCH1

Across TCGA patient cohorts, LRCH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,916 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LRCH1-associated proteins across cancer lineages are SORBS3, CNN3, and KANK2. Each is linked with LRCH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRCH1-to-partner and partner-to-LRCH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRCH1 versus SORBS3 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRCH1→partner) and Y-score (partner→LRCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SORBS3 →	+0.486	+0.686	<.001	<.001	3	7
BRCA	CNN3 →	+0.478	+0.359	<.001	<.001	3	7
BRCA	KANK2 →	+0.434	+0.567	<.001	<.001	3	7
OV	PRKG1 →	+0.717	+0.547	<.001	<.001	3	6
OV	SNX9 →	+0.423	+0.612	<.001	<.001	3	6
OV	TIMP2 →	+0.652	+0.687	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,916 associations by consensus.

LRCH1 vs SORBS3 — OV

Explore this scatter interactively →