LRCH1

Across TCGA cell cohorts, LRCH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,236 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRCH1-associated GO terms across cancer lineages are Sister chromatid biorientation, Positive regulation of lamellipodium morphogenesis, and Intra-Golgi vesicle-mediated transport. Each is linked with LRCH1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRCH1-to-partner and partner-to-LRCH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid biorientation grouped by LRCH1-low versus LRCH1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRCH1→partner) and Y-score (partner→LRCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Sister chromatid biorientation →	+0.095	+0.859	<.001	<.001	3	9
STOMACH	Positive regulation of lamellipodium morphogenesis →	+0.136	+1.024	.001	<.001	3	8
PANCREAS	Intra-Golgi vesicle-mediated transport →	+0.065	+0.575	.001	.004	2	9
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.051	+0.953	.007	.001	3	8
BLOOD_Lymphoma	Positive regulation of epithelial cell migration →	+0.065	+0.701	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of GTPase activity →	+0.029	+0.721	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,236 associations by consensus.

Sister chromatid biorientation by LRCH1 expression — BLOOD_Leukemia

Explore this box plot interactively →