Across TCGA patient cohorts, LRBA protein abundance is significantly associated with the RNA expression of many other genes, with 15,396 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LRBA-associated genes across cancer lineages are CLCN3, GFPT2, and TTC39A-AS1. Each is linked with LRBA in more than 6 cancer types. Because this analysis shows association rather than direction, both LRBA-to-partner and partner-to-LRBA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRBA→partner) and Y-score (partner→LRBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLCN3 →	+0.723	+0.480	<.001	<.001	3	7
CCRCC	GFPT2 →	-1.628	-0.243	<.001	.001	3	7
BRCA	TTC39A-AS1 →	+0.939	+0.508	<.001	<.001	3	7
BRCA	MLPH →	+2.722	+0.538	<.001	<.001	3	6
BRCA	PATJ →	+0.953	+0.575	<.001	<.001	3	6
BRCA	GLIPR1 →	-0.724	-0.430	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,396 associations by consensus.

Exploration

LRBA survival (RNA) · tumor vs normal (RNA) · all LRBA data types